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Am J Infect Control
; 41(3): 259-60, 2013 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23062579
RESUMO
We evaluated 74 children with previous fecal extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae colonization who were hospitalized and receiving a course of antibiotic therapy for suspected infection. Sixty-four patients (86.5%) received a carbapenem agent. Only 3 patients were infected with an ESBL-producing Enterobacteriaceae. Sixty-one (95%) initial antibiotic courses were considered excessive and required deescalation; however, deescalation was accomplished in only 38 patients (62%). This suggests the need for an ESBL control program to decrease carbapenem use and thereby limit carbapenem resistance in gram-negative bacilli.